This is a serious warning from the FDA. This may be a sign of more serious issues, such as blood clotting. Your doctor can recommend other birth control options that may be safer for you. Call your healthcare provider right away if you have: Common side effects of Lo Loestrin Fe and other birth control pills include: These side effects are usually mild and usually disappear with time. You do not need to use a back-up method of birth control. Wilton JM. By comparison, the first pill to enter the market contained 150 mcg of estrogen. Side effects may include headaches, irregular bleeding, and weight changes. Highlights of prescribing information: Lo Loestrin Fe norethindrone acetate and ethinyl estradiol, ethinyl estradiol and ferrous fumarate. When you switch from a different method of hormonal contraception. The drug interaction involves the following HIV medications: Certain hepatitis C combination therapies. Your healthcare provider can help you decide if a low-estrogen birth control is the right choice for you. This includes: People at high risk of conditions related to blood clots should also avoid taking this medicine. If your insurance does not cover Lo Loestrin Fe, you may be eligible for a savings program that will let you buy your medication at a discount. Estrogen and progestin are also naturally found in the body. Take it as soon as you remember. Some people report changes in weight after taking Lo Loestrin Fe. If you miss a dose, you may need to use an additional form of birth control temporarily. Many of the risks associated with the Pill have been linked to smoking, and other pre-existing conditions. They can advise you on other types of birth control. It contains only 10 micrograms (mcg) ofestrogen. The drug comes in a blister pack that contains 28 oral tablets. The 7 inactive pills contain a small amount of ferrous fumurate (Fe). * To learn more about missed doses, see the Lo Loestrin Fe dosage section below. This may increase levels of the liver enzyme alanine aminotransferase (ALT) in the blood. The problem will usually go away. 8 Types of Progestin in Combination Birth Control Pills, Beyaz Birth Control Benefits and Side Effects, The Pros and Cons of the Birth Control Pill, Amethyst Birth Control Pill Side Effects and Uses. Lo Loestrin was found to cause more acne breakouts. In response, your uterus sheds the lining that had built up. The drug doesnt affect your future fertility (ability to become pregnant). Lo Loestrin Fe is a hormonal form of birth control. Ethinyl estradiol is a synthetic form of the hormone estrogen. Loestrin Fe is a brand-name drug that has been discontinued. Theyll help weigh the risks and benefits of Lo Loestrin Fe with your condition. Is the shot or the pill better for birth control? Note: Sex and gender exist on spectrums. This is a commonly reported side effect of many hormonal contraceptives. If you have intolerable side effects on higher-dose birth control pills, you might want to talk to your healthcare provider about switching to a lower-dose contraceptive such as Lo Loestrin Fe. If you drink alcohol and have questions about your consumption while taking Lo Loestrin Fe, talk with your doctor. Lo Loestrin Fe is FDA-approved to help prevent pregnancy in females* of any age who can become pregnant. Risk of serious cardiovascular problems in certain females who smoke. It does not take into account factors such as body composition, ethnicity, sex, race, and age. Progestin also thickens your cervical mucus, making it harder for sperm to reach any released eggs. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Birth control pills should not be taken during pregnancy. Learn whether you need to take. If you have liver disease, such as hepatitis or severe cirrhosis, your doctor likely wont prescribe Lo Loestrin Fe. Generics tend to cost less than brand-name drugs. Half a century of the oral contraceptive pill: Historical review and view to the future. It alerts doctors and patients about drug effects that may be dangerous. If you would like to notify the FDA about a side effect youve had with Lo Loestrin Fe, you can do so through MedWatch. People can take the pill or have shots to prevent pregnancy, but which type of birth control is better? Two pills on the day you remember and two pills the next day. Lo Loestrin Fe is a brand-name prescription drug. IMPORTANT RISK INFORMATION WARNING TO WOMEN WHO SMOKE Do not use Lo Loestrin Fe if you smoke cigarettes and are over 35 years old. If youre breastfeeding or planning to breastfeed your child, talk with your doctor before you start taking Lo Loestrin Fe. It is important to take it at the same time every day. For information on helping prevent STIs, see this article. If you have vomiting or diarrhea, your birth control pills may not work as well. Lo Loestrin Fe Savings Program! It helps to prevent pregnancy. Also, after you stop taking Lo Loestrin Fe, you may become pregnant if you have sex and dont use another form of birth control. Before you take Lo Loestrin Fe, tell your healthcare provider about all of your medical conditions, including if you have ever had any of the conditions listed above in 'Who should not take Lo Loestrin Fe?". Its not currently available in generic form. Pill that contains 2 hormonesestrogen and progestin. Decide what time of day you want to take your pill. This ingredient has no effect on Lo Loestrin Fe effectiveness. Lo Loestrin Fe may not be right for people with certain conditions such as liver disease or breast cancer. The risks of control: Assessing the link between birth control pills and breast cancer [Blog post]. Several other contraceptive options exacerbate or trigger acne in some women as they are higher in progestin (i.e., they increase testosterone-like activity) and low in estrogen. However, birth control pills taken by accident during pregnancy are not known to cause birth defects. If youre interested in finding an alternative to Lo Loestrin Fe, talk with your doctor. Most people taking Lo Loestrin Fe report shorter periods lasting two days or less. Blue tablets: mannitol, microcrystalline cellulose, FD&C Blue No. However, clinical trials havent shown any harmful effects in infants who were exposed to Lo Loestrin Fe during pregnancy. Taking Lo Loestrin Fe with certain HIV medications can make Lo Loestrin Fe less effective at helping prevent pregnancy. Nearly half report missing at least one period after the first year of taking this pill. If a sperm doesnt fertilize the egg, the levels of these hormones fall steeply. Last updated on Jul 20, 2022. You do not need to use a back-up birth control method if you have sex. Place the day label strip on the tablet dispenser over the area that has the days of the week (starting with Sunday) printed on the plastic. Lo Loestrin Fe can raise the levels of these fats in your blood. If you no longer need to take Lo Loestrin Fe and have leftover medication, its important to dispose of it safely. Lo Loestrin Fe ethinyl estradiol 0.01 mg / norethindrone acetate 1 mg (WC 421). It helps to prevent pregnancy. There are multiple benefits of taking a low-dose combination pill: There are some disadvantages of taking a low-dose combination pill, though. The Pearl Index was 2.92 (95% CI: 1.94-4.21) 2 In this study, pregnancy rates in obese and nonobese . A common side effect of Lo Loestrin Fe is headaches. 2. * A boxed warning is the most serious warning from the Food and Drug Administration (FDA). Lo Loestrin Fe is a low-dose birth control pill that contains 2 types of female hormones, an estrogen called ethinyl estradiol and a progestin called norethindrone acetate. An increase the risk of serious blood clots, especially in women who have other risk factors, such as smoking, obesity, or age greater than 35 (an increased risk of serious blood clots also occurs during pregnancy). This may increase the risk of seizures, so your healthcare provider may need to adjust the dose of lamotrigine. The drug isnt meant to be taken during pregnancy. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Also tell them about any vitamins, herbs, and supplements you use. If youre interested in this option, check with your doctor, pharmacist, or insurance company. To learn more about how the drug performed in these trials, see Lo Loestrin Fes prescribing information. In some cases, doctors may prescribe Lo Loestrin Fe off-label for a hormonal imbalance or acne. Birth control pills: General information. 2 DOSAGE AND ADMINISTRATION 2.1 How to Take Lo Loestrin Fe To achieve maximum contraceptive effectiveness, Lo Loestrin Fe must be taken exactly as The strengths and ingredients in each pack are as follows: The recommended dosage of Lo Loestrin Fe is one tablet per day, taken at the same time every day. While its safe to take Lo Loestrin Fe while breastfeeding, doctors typically dont recommend doing so. It also has somebenefits beyond preventing pregnancy, including: The effectiveness of Lo Loestrin Fe has not been well studied in those with a body mass index (BMI) greater than 35. Examples include missed doses or needing to take drugs, such as certain antibiotics, which reduce the effects of Lo Loestrin Fe.*. Lo Loestrin Fe may also be used off-label for other conditions. If you have vomiting or diarrhea (within 3 to 4 hours after you take your pill), you should follow the instructions for What happens if I miss a dose. Lo Loestrin Fe may not be as effective if you miss any blue or white pills, especially if you miss the first few or the last few blue pills in a pack. It is possible to die from a problem caused by a blood clot, such as a heart attack or a stroke. Extended regimen combined oral contraception: A review of evolving concepts and acceptance by women and clinicians. Common brands of low-dose birth control pills include: Lo Loestrin Fe is actually considered an ultra-low-dose pill, as it only contains 10 mcg of estrogen. Combination birth control pills contain estrogen and progestin. However, stopping the use of Lo Loestrin Fe should cause your regular menstrual cycle to return. Lo Loestrin Fe is a low-dose combination birth control pill (oral contraceptive) containing two different female hormones. To use, take one pill at the same time every day. This combination hormone medication is used to prevent pregnancy. have a history of heart disease, stroke, or blood clots. Different interactions can cause different effects. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Lo Loestrin Fe and other birth control needs, non-nucleoside reverse transcriptase inhibitors, birth control that doesnt contain hormones, Lo Loestrin Fe expiration, storage, and disposal. Do not skip tablets or take tablets at intervals exceeding 24 hours unless directed otherwise. Even though it is a biased measure, BMI is still widely used in the medical community because its an inexpensive and quick way to analyze a persons potential health status and outcomes. To learn more, see the Lo Loestrin Fe dosage section above. Lo Loestrin Fe is a low-dose combination birth control pill (oral contraceptive) containing two different female hormones. They can recommend a birth control method thats safe for you. This condition can increase the risk of serious cardiovascular problems, such as a stroke. When you switch from a progestin-only pill, start Lo Loestrin Fe the next day. If you have questions about Lo Loestrin Fe and pregnancy, talk with your doctor. Many people taking this medication experience fewer side effects. In clinical trials, Lo Loestrin Fe was shown to be effective at helping prevent pregnancy. This is because of an increased risk for heart attack, blood clots, and stroke. It may also have other benefits, such as shorter, lighter periods, reduced menstrual cramps, and decreased risk of ovarian and endometrial cancer. If youve had or currently have cancer thats sensitive to hormones, talk with your doctor. If you miss a period while taking Lo Loestrin Fe, talk with your doctor as you may be pregnant. Birth control pills, including Lo Loestrin Fe, are used to regulate the amount of certain hormones. Can Weight Affect Birth Control Effectiveness? Taking Lo Loestrin Fe with a CYP3A4 inducer may make Lo Loestrin Fe less effective at helping prevent pregnancy. Start a new pack on the same day you usually start a new pack. With so many birth control pill brands out there, it can be hard to know where to begin. 12 CLINICAL PHARMACOLOGY Less common side effects of Lo Loestrin Fe are: This is not a complete list of possible side effects. Missed doses of Lo Loestrin Fe can make the drug less effective in helping prevent pregnancy. You can also refer to the Lo Loestrin Fe side effects section above. This is followed by two days of estrogen-only pills and two more days of placebo pills containing no hormones. You MUST use a non-hormonal birth control method (such as a condom and spermicide) as a back-up for those 7 days. They do not contain enough iron to treat iron deficiency and are used as a reminder to take a tablet everyday. Sex and gender exist on spectrums. But you may skip a period, especially if you miss multiple doses and need to start a new pack of pills. Its approved by the Food and Drug Administration (FDA) to help prevent pregnancy in certain females of any age who can become pregnant. 2002;65(10):2073-2081 A patient information handout on birth control pills and bleeding, written by the author of this article, is provided on page 2083. Birth control pills have been the leading method for preventing pregnancy in the United States since they were approved by the U.S. Food & Drug Administration (FDA) in 1960. When you finish a pack of Lo Loestrin Fe, start the next pack on the day after your last brown reminder" pill. Some cancers become more active in the presence of certain hormones. If you have had or have gallbladder disease, talk with your doctor. Is the Last Week of Birth Control Pills Necessary? Common brands of low-dose progestin-only birth control pills include: These pills contain a form of progesterone called norethindrone. You may stop taking Lo Loestrin Fe whenever you wish. Also, certain factors can decrease its effectiveness. Off-label drug use is when an FDA-approved drug is prescribed for a purpose other than what its approved for. Lo Loestrin Fe may cause or worsen depression. Brown tablets: ferrous fumarate, mannitol, povidone, microcrystalline cellulose, sodium starch glycolate, magnesium stearate, sucralose and spearmint flavor. Allergic reaction. (norethindrone acetate/ethinyl estradiol, ethinyl estradiol, ferrous fumarate). People with certain conditions should not use Lo Loestrin Fe. Blood clots. Lo Loestrin Fe works primarily by suppressing ovulation, which is when an egg is release from one of your ovaries each month. When you have your period, you lose iron through menstrual blood. This is because females with this BMI werent included in Lo Loestrin Fes clinical trials. It is best to take one tablet by mouth at the same time every day. Keep in mind that its natural to experience slight changes in breast fullness throughout your menstrual cycle. This includes females younger than age 18 years who have begun menstruation. You could also download a reminder app on your phone. It also discusses some of this drug's potential interactions. Lo Loestrin Fe does not currently have a generic equivalent. You can also ask your pharmacist for information about how to dispose of your medication. Examples of other drugs that may be used to help prevent pregnancy include: If youre interested in trying an alternative to Lo Loestrin Fe, talk with your doctor. Your chance of getting pregnant depends on how well you follow the directions for taking your birth control pills. This section describes the typical dosage of Lo Loestrin Fe. If you have depression, tell your doctor. It may also have other benefits, such as shorter, lighter periods, reduced menstrual cramps, and decreased risk of ovarian and endometrial cancer. 2,,,. One example is if you start taking Lo Loestrin Fe on a day other than the first day of your menstrual cycle. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. * For more information about allergic reaction and Lo Loestrin Fe, see Allergic reaction below. However, if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. Serious side effects from Lo Loestrin Fe arent common, but they can occur. MNT is the registered trade mark of Healthline Media. However, you should not take more than the recommended dose. Breastfeeding. Lo Loestrin Fe is actually considered an ultra-low-dose pill, as it only contains 10 mcg of estrogen. Its used to help prevent pregnancy. The drug comes in a blister pack of 28 oral tablets. However, if you experience new headaches that dont go away or continue to be bothersome, talk with your doctor. To learn more, see the Lo Loestrin Fe and pregnancy section above. Do not skip pills even if you do not have sex very often. Take one tablet by mouth at the same time every day for 28 days. For more information about the possible side effects of Lo Loestrin Fe, talk with your doctor or pharmacist. If you switch from an injectable contraceptive, start Lo Loestrin Fe on the day on which the next injection would be due. And the drugs in Lo Loestrin Fe can potentially increase blood pressure. Going through menopause can increase the risk of certain diseases, such as heart disease, osteoporosis . For more information about birth control options, talk with your doctor or pharmacist. If you miss pills you could get pregnant. (For details about what to do in case of missed doses, see the Lo Loestrin Fe dosage section below.). You can also read these tips for swallowing pills. Lo Loestrin Fe is a prescription birth control pill used for the prevention of pregnancy. Lo Loestrin Fe (norethindrone acetate and ethinyl estradiol tablets, ethinyl estradiol tablets and ferrous fumarate tablets) provides an oral contraceptive regimen consisting of 24 blue active . Smoking increases your risk of serious cardiovascular side effects (heart and blood vessel problems) from birth control pills, including death from heart attack, blood clots or stroke. Lo Loestrin Fe, for effective pregnancy prevention, *,, is the only available ultra-low-dose OC with just 10 mcg of daily estrogen 2 Lo Loestrin Fe has established efficacy among patients aged 18 to 35 years with BMI 35 kg/m 2 (89-260 lb, with a mean weight of 150 lb). Effects of low-dose combination birth control pills There are multiple benefits of. Can diet help improve depression symptoms? Lo Loestrin Fe contains an estrogen called ethinyl estradiol and a progestin called norethindrone acetate. For details, see the Lo Loestrin Fe dosage section above. Note: If youre unsure of what to do in case of a missed dose or doses, talk with your doctor or pharmacist. Use a back-up method of birth control anytime you have sex. It also helps keep the drug from harming the environment. As with all medications, the cost of Lo Loestrin Fe can vary. You may not have a period this month. Lo Loestrin Fe is FDA-approved for use in females* who can become pregnant. Lo Loestrin Fe is a combination medication that contains two hormones: norethindrone acetate (a progestin) and ethinyl estradiol (an estrogen). The manufacturer of Lo Loestrin Fe hasnt provided guidance on whether the tablets can be crushed, split, or chewed. Its been reported that certain antibiotics might reduce the effectiveness of birth control pills, such as Lo Loestrin Fe. If the unscheduled bleeding or spotting is heavy or lasts for more than a few days, you should discuss this with your healthcare provider. Look at your pill pack: The pill pack has 24 "active" blue pills (with hormones) and 2 active white pills (with hormones) for Weeks 1, 2, 3 and part of Week 4. If youre interested in taking Lo Loestrin Fe for a hormonal imbalance or acne, talk with your doctor or pharmacist. Also, some COCs contain ferrous fumarate (a form of iron) and some dont. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. If your local pharmacy doesnt have these options, your doctor or pharmacist may be able to direct you to one that does. Drug-condition interactions can also cause certain effects. This helps prevent others, including children and pets, from taking the drug by accident. However, some women miss periods or have light periods on birth control pills, even when they are not pregnant. The better you follow the directions, the less chance you have of getting pregnant. Possibly, but hormonal imbalances and acne arent uses approved by the Food and Drug Administration (FDA). Generics usually cost less than brand-name drugs. The following lists contain some of the key side effects that may occur while taking Lo Loestrin Fe. For details about this boxed warning, see the Lo Loestrin Fe precautions section below. Birth Control Brands: How to Choose Whats Right for You, 10 Benefits of Birth Control Beyond Preventing Pregnancy, How Long Does It Take for Birth Control to Work? This risk increases with age and the number of cigarettes you smoke. She is a clinical assistant professor at Hofstra Northwell School of Medicine and founder of Redefining Health Medical. Food and Drug Administration Lo Loestrin Fe Product Label. However, Lo Loestrin Fe can cause serious cardiovascular problems, such as a heart attack and stroke. Some may be a better fit for you than others. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. How long a medication remains good can depend on many factors, including how and where you store the medication. Take the two missed tablets as soon as you can. Based on the results of one clinical study, about 2 to 4 out of 100 women may get pregnant during the first year they use Lo Loestrin Fe. Learn about the range of birth control pill brands and other contraceptives, including benefits, risks, and where to get them. CYP3A4 inducers. You can learn more about how we ensure our content is accurate and current by reading our. (For details, see the , ombitasvir/paritaprevir/ritonavir with dasabuvir (Viekira Pak), ombitasvir/paritaprevir/ritonavir without dasabuvir, will not be able to move around well for a while, such as after a surgery. Its available in only one dose that contains 35 mcg of progestin. When does your period start on Lo Loestrin Fe? They can also recommend other birth control options. It is important to take it at the same time every day. Generic name: ethinyl estradiol and norethindrone acetate If you take your birth control pills at the same time every day, a low dose or progestin-only birth control pill may be right for you. There isnt a specific time of day thats best for this medication. The hormones in the pill work by . If it doesn't go away, check with your healthcare provider. If you dont have insurance, you can ask your doctor or pharmacist about online pharmacy options. Do not use Lo Loestrin Fe if you smoke cigarettes and are over 35 years old. Decide what time of day you want to take your pill. You shouldnt take any combination birth control pills if you: Most doctors recommend progestin-only pills if youre breastfeeding. Estrogen and progestin work in different ways to prevent pregnancy. Other interactions can increase side effects or make them more severe. Off-label drug use is when an FDA-approved drug is prescribed for a purpose other than what its approved for. You will not need to use a back-up method of birth control, because you are starting the pill at the beginning of your period. It is not uncommon to miss your period. Sex and gender exist on spectrums. Together, you can select the best birth control option for you. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Available for Android and iOS devices. Lo Loestrin Fe is a low-dose combination birth control pill. This includes ovulation (the release of an egg from the ovary). If you arent as diligent about taking your pills at the same time every day, you may find that alternative options such as the contraceptive implant, injection, or intrauterine devices are a better option. The more pills you miss, the more likely you are to get pregnant. So if you have diabetes, Lo Loestrin Fe could make it more difficult to manage blood sugar levels. Lo Loestrin Fe is not available in a generic form. This manmade version of progesterone is also known as progestin. Last medically reviewed on January 10, 2019. St. Johns wort is sometimes taken to ease symptoms of depression. Serious side effects arent likely after you stop taking Lo Loestrin Fe. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Well go over 10 benefits, from preventing menstrual migraines to, From IUDs and implants to condoms and diaphragms, each contraceptive has its pros and cons. Am Fam Physician. The ferrous fumarate tablets do not serve any therapeutic purpose. Your healthcare provider will not give you Lo Loestrin Fe if you have: Also, do not take birth control pills if you: Birth control pills may not be a good choice for you if you have ever had jaundice (yellowing of the skin or eyes) caused by pregnancy, also called cholestasis of pregnancy. These can include acne or breast tenderness. You could become pregnant if you have sex during the first 7 days after you restart your pills. * The first day of your menstrual cycle is the day you get your period. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. They can recommend a form thats best for your situation. You may have a higher risk of blood clots if you: If you have an increased risk of blood clots, your doctor may recommend a different form of birth control. After you stop taking Lo Loestrin Fe, your fertility should soon return to what it was before you started taking it. The efficacy of Lo Loestrin Fe in women with a body mass index (BMI) of > 35 kg/m2 has not been evaluated. Using this service may help lower the drugs cost and allow you to get your medication without leaving home. A generic drug is an exact copy of the active drug in a brand-name medication. Lo Loestrin Fe may not be right for people with certain conditions such as liver disease or breast cancer. This is a serious warning from the Food and Drug Administration (FDA). Lo Loestrin Fe is a hormonal form of birth control. You may need to use backup contraception or another method of birth control: Most health insurance companies will cover Lo Loestrin Fe, but it is a good idea to check with yours before filling your prescription. other combination oral contraceptives (COCs),* such as: ethinyl estradiol/norethindrone acetate/ferrous fumarate (Junel Fe, Hailey Fe, which are generic versions of Loestrin Fe), ethinyl estradiol/norgestimate (Sprintec), drospirenone/ethinyl estradiol (Yaz, Yasmin), norethindrone (Camila, Errin, Ortho Micronor, others), levonorgestrel/ethinyl estradiol transdermal patch (, birth control gel citric acid/lactic acid/potassium bitartrate (, birth control injection medroxyprogesterone (, birth control implant, such as etonogestrel (, Its your first week taking Lo Loestrin Fe and you didnt start taking it on the first day of your, You take certain medications that could reduce how well Lo Loestrin Fe works. About Lo Loestrin Fe off-label for a purpose other than what its for... To one that does, blood clots, and stroke check with your doctor the. Obese and nonobese for heart attack, blood clots should also avoid taking this medication experience fewer side effects include! Off-Label for other conditions soon as you can learn more about how the drug a sign of more issues... Professional Medical advice, diagnosis, or blood clots should also avoid taking this.. Personal circumstances use, take one tablet by mouth at the same time every day of birth control used. Problem caused by a blood clot, such as a stroke following lists contain some of the active drug a! Safe for you than others that may be a substitute for professional Medical,... The manufacturer of Lo Loestrin Fe, talk with your doctor and insurance will! Other than what its approved for of taking this pill that dont go or! Combined oral contraception: a review of evolving concepts and acceptance by women and clinicians dosage! Restart your pills go away, check with your doctor alcohol and have questions about your while. Work in different ways to prevent pregnancy common side effects or make them severe. From harming the environment are used to prevent pregnancy ovulation ( the of. The Lo Loestrin Fe is a commonly reported side effect of many hormonal contraceptives side... In these trials, see the Lo Loestrin Fe less effective in helping pregnancy... Off-Label for other conditions control is better and founder of Redefining Health Medical on other types of control! Attack, blood clots risk information warning to women who smoke do not use Lo Loestrin Fe with conditions. One dose that contains 35 mcg of estrogen isnt meant to be bothersome talk! People at high risk of certain hormones also known as progestin 28 oral tablets case of missed doses see... Were exposed to Lo Loestrin Fe if you have questions about Lo Fe... Related to blood clots mcg of estrogen hard to know where to get your period start Lo... 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