Furthermore, high supplemental doses of zinc ( 50 mg/d) over the long term can cause copper deficiency. The aqueous phase was then heated at 70-80C and dimethyl sulfoxide (remaining part), polyoxyl 35 castor oil, gellan gum, and benzalkonium chloride were added under stirring. INDICATIONS AND USAGE It is a pale yellow oily liquid that is clear at temperatures above 26 C. Together with fatty acid glyceryl polyglyceryl esters, they form the hydrophobic part of the product. It is insoluble in water, soluble in chloroform and slightly soluble in ethanol. 1g 10g 50g $ 0.00 Add to Cart ORDERING INFORMATION International TAICLONE BIOTECH CORP. order@taiclone.com +886-2-2735-9682 . It is made by reacting castor oil with ethylene oxide in a molar ratio of 1:35. CAS No: 61791-12-6 Form: Colourless Oil Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly . administration) for poorly-water soluble pharmacological agents. 3523 NF Monographs: Polyoxyl 40 Hydrogenated Castor Oil. Alkasurf CO 10. Polyoxyl 35 Castor Oil (USP-NF) August 2019 | Supersedes issue dated December 2018 | Last change WF-No. Request a sample Polyoxyl 35 Castor Oil contains mainly the tri-ricinoleate ester of ethoxylated glycerol, with smaller amounts of polyethylene glycol ricinoleate and the corresponding free glycols. Copper and zinc . IN EN. . Arzneimittelforschung. Read More Both copper and zinc are imperative for optimal immune health, including internal and external healing. Composition The main component of Kolliphor EL is glycerol polyethylene glycol . But, zinc can interfere with copper absorption. It has a . as oil, Cremophor EL (polyoxyl 35 castor oil) as surfactant, and hydrophilic polymer PEG 3350 as solid matrix. . The main constituent of this product is glyceryl polyethylene glycol oxystearate. On the other hand, if the emulsifier is not very polar, then your oil phase should be more comprised of apolar oils, such as alkanes like squalane, or undecane . Drug solution phase was then added dropwise into the aqueous phase under continuous stirring process. Polyoxyl 35 castor oil; Polyoxyl 40 castor oil Glow Eluxe Haircare Australia is a one of a kind shampoo & conditioner system that will leave your hair and scalp feeling cleaner . [1] It is a colourless or pale yellow liquid with a distinct taste and odor. VitiPure HCO 40 is versatile non-ionic solubilizer and emulsifier enhancing the solubility and bioavailability of hydrophobic APIs and fat-soluble vitamins. Answered by: TechService7. Polyoxyethylene castor oil derivatives are non-ionic solubilisers and emulsifiers used in oral formulations. Polyoxyl 35 castor oil United States Pharmacopeia (USP) Reference Standard; CAS Number: 61791-12-6; Synonyms: Castor oil, ethoxylated,PEG 35 castor oil; find USP-1547200 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich. Polyethylene glycol (5) hydrogenated castor oil. DAWF-2019-0819 03_111139e-04/Page 1 of 5 . Alkamuls EL 620. Some medium to high polarity oils include C12-15 alkyl benzoate, caprylic/capric triglycerides, octyldodecyl myristate, castor oil, and coco-glycerides, among countless others. Price: $27.90 - OR - Add to Wish List Add to Compare Based on 0 reviews. AQ 250. 3526 NF Monographs: Polysorbate 40. Polyethylene glycol (45) hydrogenated castor oil. Composition: Castor Oil 56.03%, n-Heptane 43.97% Density: 0.77 Color: Colorless liquid Physical State: Liquid Solubility Information: Insoluble Shelf Life: 24 Months Storage: Ambient . Actinol CS 40. Polyoxyl castor oil. VitiPure CO 35 is a non-ionic solubiliser and emulsifying agent for the human and veterinary pharmaceutical industries. Castor oil polyoxyethylene ether.
Packaging and storage Preserve in tight containers. This technique has a mechanism for increasing the surface area of the drug as well as wetting from the addition of non-volatile solvents resulting in a lower surface tension and contact angle, so. G Cornaire, J F Woodley, S Saivin, J Y Legendre, S Decourt, A Cloarec, G Houin. Solubility O) Partition Coefficient: n-octanol/water P) Auto-Ignition Temperature No data available No data available No data available
tctc691376 Polyoxyl 35 Castor Oil. .His nonprescription medications included ascorbic acid 250 mg orally once daily and zinc sulfate 220 mg orally once daily for wound healing. Alkasurf CO 40. and i.v. POE (16) hydrogenated castor oil | C63H122O15 | CID 154733642 - structure, chemical names, physical and chemical properties, classification, patents, literature . Polyoxyl 40 hydrogenated castor oil is a non-ionic solubilizer and emulsifying agent that is obtained by reacting hydrogenated castor oil with ethylene oxide [ 13 ]. CLINICAL PHARMACOLOGY Vitamin K1 Injection (Phytonadione Injectable Emulsion, USP) aqueous dispersion of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring . Polyoxyl (35) Castor Oil. Atlas G 1281. Synonym(s): Cremophor EL; Macrogolglycerol ricinoleate; PEG-35 castor oil; Polyoxyl 35 hydrogenated castor oil; Polyoxyl-35 castor oil MDL . Buy Polyoxyl 35 Castor Oil (CAS 61791-12-6), a biochemical for proteomics research, from Santa Cruz Biotechnology. The reversible conversion of carbonic acid to carbon dioxide plays an important role in maintaining a blood pH of 7.40. It results from the reaction of glycerol ricinoleate with about 35 moles of ethylene oxide. PMID: 10918954. BASF polyoxyl 35 castor oil Polyoxyl 35 Castor Oil, supplied by BASF, used in various techniques. Polyoxyl 35 Castor Oil. Arlatone 650. . Polyoxyl 35 Castor Oil contains mainly the tri-ricinoleate ester of ethoxylated glycerol, with smaller amounts of polyethylene glycol ricinoleate and the corresponding free glycols. Polysorbate 80 and Cremophor EL (polyoxyl 35 castor oil) are such surfactants but they may also modulate the action of P-glycoprotein, an energy-dependent "counter-transport" system implicated in the phenomenon of multidrug resistance in cancer cells. Polyoxyl n castor oil (n=36) (synonyms: ethoxylated castor oil, polyethylene glycol castor oil) is a mixture of triricinoleate esters of ethoxylated glycerol with small amounts of polyethyleneglycol (macrogol) ricinoleate and the corresponding free glycols. DEFINITION Polyoxyl 35 Castor Oil contains mainly the triricinoleate ester of ethoxylated glycerol with smaller amounts of polyethylene glycol ricinoleate and the corresponding free glycols. For oral formulations, it works well as a solubiliser in aqueous and hydroalcoholic solutions for fat soluble vitamins, essential oils and other hydrophobic drugs.
Castor oil, ethoxylated. Good permeation is a prerequisite for molecules . 1Effect of Polyoxyl 35 Castor Oil and Polysorbate 80 on the Intestinal Absorption of Digoxin in Vitro. At room temperature it appears as pale-yellow oily liquid. It results from the reaction of glycerol ricinoleate with about 35 moles of ethylene oxide. Alkamuls OR 36. Applications Products Services Support.
undefined. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages. Browse Polyoxyl 35 castor oil and related products at MilliporeSigma. Super Refined P35 Castor Oil is a castor oil derivative, resulting from the reaction of glycerol ricinoleate and 35 mols of ethylene oxide. Polyoxyl 35 castor oil, appearance: pale yellow, oily liquid at temperatures above 26C ; HLB: 12 - 14 ; Polyoxyl 40 hydrogenated castor oil, appearance: white to yellowish, semisolid paste at temperature above 30C ; HLB: 14 - 16 ; Polyoxyl 60 hydrogenated castor oil, appearance: white paste at room temperature ; HLB: 15 - 17
Know about technical details of Polyoxyl 35 Castor Oil like: chemical name, chemistry structure, formulation, uses, toxicity, action, side effects and more at Pharmacompass.com. Disclosed herein are novel formulations containing relacorilant ((R)-(1-(4-fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1H-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone) that are suitable for administration, including oral administration, to patients suffering from disorders amenable to treatment by glucocorticoid receptor modulators .
4, Further explanation (a), On physical and chemical indexes: firstly, shall be indicated carbon atom distribution; secondly, shall be indicated average molecular weight. Polyoxyl 35 Castor oil is included in the FDA Inactive Ingredients Database (covering IV injections and ophthalmic solutions). Solubility : soluble in water, ethanol 2-propanol, ethyl acetate, n-propanol, chloroform, carbon tetrachloride, tolune & xylene. Product Detail Company Info Product Specs Item Super Refined P35 Castor Oil Next, this can be added to the water phase. PEG 40 HYDROGENATED CASTOR OIL SOLUBILITY When adding PEG 40 Hydrogenated Castor Oil to cosmetics formulations, it can be blended in its cold state directly into the oil phase at a suggested ratio of 3:1 (PEG 40 Hydrogenated Castor Oil to oil). 3527 NF Monographs: Polysorbate 60. Polyoxyl 40 Hydrogenated Castor Oil or Macrogolglycerol Hydroxystearate also referred to as Cresol RH 40 is a non-ionic solubilizers and emulsifying agents that is obtained by reacting hydrogenated castor oil with ethylene oxide. Polyoxyl castor oil (polyethoxylated castor oil, Kolliphor EL, or Cremophor EL) is prepared by reacting ethylene oxide with castor oil in a ratio of 35:1. Carbonic acid is the main buffering compound in human blood and can be broken down to carbon dioxide by an enzyme called carbonic anhydrase. Polyoxyl 35 castor oil [NF] Synonyms. . SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES: : US15094732: : 2016-04-08: (): US20170014382A1: (): 2017-01-19: : B Synonyms: Castor oil, ethoxylated. Choose a Store . The solubility increases with the increase of EO number. Order Now. Advantages Versatility Tasteless Colourless and transparent Reduces consumption Stable over a wide temperature range Self shining Highly hydrophilic Improves foam stability pH independent Elegant and Polyoxyl 35 Castor Oil USP monographs. AVAILABLE SIZES. They work closely together to improve wound elasticity and resistance. Chemical Name Polyoxyl 35 Castor Oil Catalogue # P689395 Company Toronto Research Chemicals 2 Brisbane Road Toronto, ON M3J 2J8 CANADA Telephone FAX Email +14166659696 . Bio-Soft HR 55. Its boiling point is 313 C (595 F) and its density is 0.961 g/cm 3. For oral formulations, it works well as a solubiliser in aqueous and hydroalcoholic solutions for fat soluble vitamins, essential oils and other hydrophobic drugs. Search Substances. 3530 USP Monographs: Polyvinyl Alcohol. Polyoxyl 35 castor oil 61791-12-6 2- [1,3-bis [2- [ (Z)-11-hydroxyheptadec-8-enoxy]carbonyloxyethoxy]propan-2-yloxy]ethyl [ (Z)-11-hydroxyheptadec-8-enyl] carbonate 3 Chemical and Physical Properties 3.1 Computed Properties 3.2 Experimental Properties 3.2.1 Physical Description Clear light yellow liquid; [Sigma-Aldrich MSDS] Chemical nature Kolliphor EL is a nonionic solubiliser and emulsifier made by reacting cas tor oil with ethylene oxide in a molar ratio of 1 : 35. 2000 Jun;50(6):576-9. The Resulting Product Is A Mixture; The Major Component Is The Material In Which The Hydroxyl Groups Of The Castor Oil Triglyceride Have Ethoxylated With Ethylene Oxide To Form Polyethylene Glycol Ethers. . This results in a compound in which the hydroxyl groups of the castor oil triglyceride are ethoxylated, forming polyethylene glycol ethers [1 ]. Packaging and storage Preserve in tight containers. Description. Alkasurf CO 15. including emulsification of fat-soluble vitamins, A, D, E, and K. Polyoxyl 35 Castor oil has been used to successfully formulate a wide variety of BCS IV hydrophobic drugs, including anaesthetics, photosensitisers . Polyoxyl 35 castor oil; Polyoxyl 40 castor oil Login . 3529 NF Monographs: Polyvinyl Acetate Phthalate. . Polyoxyl 35 Castor Oil Catalog No: tctc691376 Available Sizes Size: 1g Size: 10g Size: 50g Specifications Application: Polyoxyl 35 Castor Oil is a triglyceride fatty acid which has the potential to repel insects and promote plant growth. Polyoxyl 40 castor oil. 3524 NF Monographs: Polyoxyl 40 Stearate. MAYUMI Squalane Oil: rated 4 out of 5 on MakeupAlley. Find Polyoxyl 35 Castor Oil & other pharma excipients for Solubilizers dosage forms on PharmaCompass. Regulatory status Meets currrent Macrogolglycerol Ricinoleate Ph. Solubility Kolliphor EL forms clear solutions in water. USP Reference Standards for Purchase USP Methyl Linoleate RS The disclosure features non-irritating pharmaceutical compositions containing CD101 in pharmaceutical acceptable salt (e.g., CD101 acetate) or neutral form. Solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) 3525 NF Monographs: Polysorbate 20. Technical inquiry about: 45-1547200 Polyoxyl 35 Castor Oil. Polyoxyethylene castor oil derivatives are non-ionic solubilisers and emulsifiers used in oral formulations. It results from the reaction of glycerol ricinoleate with 35 mol of ethylene oxide. It is also soluble in many organic solvents, e.g.ethyl alcohol, n-propyl alcohol, isopropyl alcohol, ethyl acetate, chloroform, carbon Eur. It forms clear solutions in water. 3528 NF Monographs: Polysorbate 80. This product is a liquid nonionic solubiliser and emulsifier, characteristic of a slightly yellow hue, and is intended for use in parenteral, ophthalmic, oral, and topical applications. Warfarin, a commonly prescribed vitamin K antagonist, interferes with the cyclic interconversion of vitamin K and its 2,3 epoxide. Overview Substance Hierarchy Substance Modifications Names and Synonyms 19 Codes - Classifications 2 Codes - Identifiers 8 Notes 1 References 24 Audit Information Date published: 2017-02-13. Mix . - Carbomer Is A Polyethoxylated Castor Oil. At the room temperature it appears as white to yellowish . ZERO BIAS - scores, article reviews, protocol conditions and more [2] It includes a mixture of triglycerides in which about 90% of fatty acids are ricinoleates. Kolliphor EL is a non-ionic solubilizer and emulsifier made by reacting castor oil with ethylene oxide in a molar ratio of 1:35. Polyoxyl castor oil. 4 Physical and Chemical Properties Physical and chemical properties of PEG-30, -33, -35, -36, -40 castor oil and PEG-30 and -40 hydrogenated castor oil can be found in the original safety assessment.1 A supplier reports that PEG-30,-35, and-40 are pale yellow viscous liquids at 30 C and have a maximum water content of 0.2%.4 PEG-40 hydrogenated castor oil is reported CAS 61791-12-6. Super Refined P35 Castor Oil from Croda Pharma A multi-compendial, high purity polyoxyl 35 castor oil that is ideal for use as an emulsifier and solubiliser for poorly water-soluble APIs in a wide range of applications, including oral SEDDS/SMEDDS formulations. If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. | Write a review Description specifications references Reviews (0) Related Products (17) Squalane Sugar Cane About Sugar cane Squalane in skin care Squal a ne, under its natural form, squal e ne, occurs in the natural skin excretion called sebum. Arlatone 285. Polyoxyl 35 Castor Oil, sc-476281, is slightly soluble in chloroform or ethyl acetate. Solubility slightly soluble in water (dispersible in water) to soluble in water. All of the patient's home medications were continued during. Bioz Stars score: 86/100, based on 19 PubMed citations. A mixture of polyoxyethylated triglycerides, by reacting castor oil with ethylene oxide in a molar ratio of 1:35, that acts as a nonionic surfactant and serves as a formulation vehicle (p.o. It has a faint but characteristic odor. (35) hydrogenated castor oil. 100W B: Dissolve about 0.1 g in 10 mL of alcoholic potassium T /W U hydroxide TS, boil for about 3 minutes, and evaporate to dry-in which W ness. Excipients Solubilizers Emulsion Polyoxyl 35 Castor Oil POLYSORBATE 80 POLYOXYL 40 HYDROGENATED CASTOR OIL MEDIUM CHAIN TRIGLYCERIDES PROPYLENE GLYCOL PYRROLIDONE GLYCERYL MONOSTEARATE CETEARETH-12 POLYOXYL 15 HYDROXYSTEARATE - Solubility Assessment & Enhancement - Sterile Liquid Formulation - Structure Elucidation - Taste Masking - Clinical Trials Alkasurf CO 25B. Calculate the percentage of ethylene oxide USP Polyoxyl 35 Castor Oil RS in the portion of Polyoxyl 20 Cetostearyl Ether taken by the Identification formula: A: Infrared Absorption 197F. Molecular Weight null.
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