I'll be starting this Thursday and have 10 steroids to take Wednesday night and then whatever they give me as pre-meds. The one time I threw up was after my second round. (And day 12 after my third and final Tax - I'd probably still say the same. For cycle 2 I used a great mouthwash - Difflam and have had no sore mouth problems since. I mentioned this thread to her - the common wisdom that the first is the worst because of the uncertainty and the rest is more of the same, only more so. In some cases, you might feel extra hungry or gain weight. We needed to make a spread sheet of what pills to take and when. It's horrid and depressing. In its mechanism of action, Taxotere prevents the inner structures of cancer cells from building, which stops cell division and eventually leads to cancer cell death. I have a good support system at home who do just about everything as I have been bed or sofa bound for the last 10 days with just small walks around the house to keep the circulation going. When working in your yard, wear protective clothing including long pants and gloves. 2.6 Premedication Regimen. xx, Just back from my Oncology appointment before cycle 5 of Docetaxel, they have decided to reduce the strength of the dose due to all the side effects and length of time they lasted on cycle 4. Drank gallons of water to try and flush it out. Your hair may become thin, brittle, or may fall out. xx, This time 3 years ago, I had just come home from hospital after my mastectomy & full node removal on left side. Use of this online service is subject to the disclaimer and the terms and conditions. Perseverance!! That's really great that she had that positive response though, seems worth it and hopeful for the rest of us! It belongs to a drug class called taxanes. Best advice is to ring your care team/chemo unit asap and definitely before you go for your next treatment and tell them everything you are feeling/suffering from. Scared to the point of not being able to sleep properly. Alternative therapies can help for relaxation althrough at th emoment i go for the glass of wine cure. I haven't been able to do anything. Any suggestions for the pain? Hope you are well now too. If you ask about people's favourite CPAP machine, you can find those who love an APAP instead. Thanks for being such a grand support for her. worst daysfor me it was the week after the infusion..I just fall apart.tired, ache, intestinal issuesetc. The care I have had from diagnosis to today has been quick, I begin Radiotherapy begining of March. My wonderful wife took me away between chemo and Rads, it was a truly enjoyable break, 5 days in a cabin in the woods (provided free by The Willow Foundation). They get worse with each cycle. The Complete Guide That Makes Choosing an HVAC Company Simple, Best Broome Tours: A Guide to This Australian Charm. You'll get there too. This typically begins two to three weeks after treatment starts. I was severely feverish, my whole body ached to the point that I felt like I was in a can crushing machine, I felt sick and my mouth was worse than ever (it had been bad all the way through). I had the FEC-T chemo first, from December 2013 to April 2014. Your labs will be closely monitored prior to each dose of docetaxel and the dose may be decreased or held if your liver function is not normal. Sending massive hugs as I know just how you feel. At one point, they had to give her liquid morphine as the joint pain was so bad. Worst days when i was on 3chemo meds, taxotere, carbon, and Herceptin, were 3-5 days after. I need to focus on this and get back on track. The only things I could taste were sweets. Performing regular mouth care can help prevent or manage mouth sores. Some chemotherapy medications can cause neuropathy (numbness or tingling in your hands and feet). It really helps to have these words of encouragement and support. Will try the mouthwash as that is also a problem, I have a drink and seconds later my mouth is so dry again! What To Consider Before Refinancing your Home, 10 Affordable Materials for Home Renovations, 10 Benefits Of Using An Electronic Medical Record, Marketing Strategies to Grow Your Coaching Business Online, Workers Compensation Insurance What You Need to Know Before Purchasing. Re: Docetaxel help please!! Thank you, hope you continue to be well. Many women who receive taxane -based chemotherapy to treat breast cancer experience long-term peripheral neuropathy, according to follow-up data from a large clinical trial. Can eat, not been sick, not taken antisickness meds, but nausia with ukky taste but poor sleep got worse. I do have to rest far more than I used to, although I manage to cope with a busy full time job. It helps with pain so uncomfortable in spasms but endurable if I dont climb too many stairs with lead legs, It may have helped the mouth too, the stronger dose did make me reach for the bonjella where moments before was ok. 10 days of horrible tastes and softer foods has been hard. This hair loss can be all body hair, including pubic, underarm, legs/arms, eyelashes, and nose hairs. I don't think you have "gone wrong" anywhere, more that T has hit you hard and you would like to be in a better place for the next 2. You have been a big help with your message of support. I am still needing sofa days, but hoping to get out soon for a much needed change of scenery and breath of fresh air. Best of luck to you all xxx, I would be happy to receive news and updates from Cancer Chat, NICE suspected cancer referral guidelines, Cancer Research UK for Children & Young People. Since the growth of normal cells may also be affected by docetaxel, other unwanted effects will also occur. Other effects for me are tingling in feet, skin peeling off, mostly in feet, toe nails highly sensitive. You will be given a corticosteroid prior to the infusion to prevent severe fluid retention and allergic reactions. You are not alone in this. Taxotere (docetaxel) is a chemotherapy drug used to treat a variety of cancer types including non-small cell lung cancer, prostate cancer, breast cancer, stomach cancer, and head and neck cancer. xx, My consultant reduced my injection strength so I had to endure 10 injections as prescribed. No wonder you were dreading it. Edema happens when fluid collects under your skin and within the tissues outside your circulatory system. Taxotere is a mitotic inhibitor that interferes with your bodys cell division process. What Is the Taxotere Mechanism of Action? The median overall survival (OS) was 81 months . This can get progressively worse with additional doses of the medication. Dragged myself to picc line clean at hospital.bad mistake, will have district nurse call next time. This is usually mild to moderate and I find that most patients are able to continue many of their regular activities. Yesterday I finally got these problems under control. I often feel like it's too much and want to give in. Any comments, please. It is a horrid drug and going through the side effects of chemo is just unbearable at times (for me and some others unfortunately!). Sorry to hear your wife suffered as she did. Got better on Day 6 and got better on Day 7. some were bad and some were tolerable plus i also had insomnia because of the steriods.Tell Donna to hang in thereand good luck to you Bob! If this were to happen, the only fix is an invasive surgery. It takes the edge off the pain which means taking paracetamol with it actually works. Docetaxel is its generic name, and it belongs to the taxane class of drugs. TAXOTERE safely and effectively. A little morning nausea for first week, a few headaches and sore lips. For obvious reasons, Saturday is the best day of the week because it's a holiday and the next day too is a holiday, followed by Friday because it's preceded by two holidays. On Taxol I was comnpletely exhausted on days 2 - 6 and napping/resting did not help at all. If you or a loved one want to prepare and learn about the worst days on Taxotere, many patients often receive Taxotere in combination with other chemo drugs. Like many have stated, I was OK for the two days following and then felt like sh*t for two or three days and then was on the mend and better until the next treatment. I have to agree, as much as I dont want to get off the couch.. Your fingernails/toenails may become dark, brittle or fall off. If you feel unwell or have any of these signs, tell them straight away. Avoid drinking alcohol on the day of your Taxotere injection. The use of scarves, wigs, hats, and hairpieces may help. xxx. This combination of meds had the remarkable result of shrinking my very large tumor by a full 50 percent! I was given Co-Codomol 500mg at the hospital when my temperature spiked. Doctors may lower the dose or prescribe drugs that reduce the risk of allergic reactions to deal with these types of side effects. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. If red meat is a problem, eat chicken, turkey, eggs, dairy products, and fish without a strong smell. Paracetamol not helping at all I could scream! . My doctors have been very good and have assured me that they caught it early. After that, I have been okay - really tired and nothing tastes good so I am not eating well - but I learned from my first course of chemo that ended in April that I need to sleep when I am tired, so sometimes when I get home from work, I go right to sleep. My own experience to date As of day 8 after my first Tax blast, I currently hate Tax and FEC in equal measure. Docetaxel can cause your body to hold too much fluid, which can be a serious side effect. If youre considering taking Taxotere to treat your cancer, you need to be prepared for what might come. love and hugs.Lorrie. I hope your teeth are in good condition. TAXOTERE is sterile, non-pyrogenic, and is available in single-dose vials containing 20 mg (0.5 mL) or 80 mg (2 mL) docetaxel (anhydrous). Do not take aspirin (salicylic acid), non-steroidal, anti-inflammatory medications (NSAIDs) such as Motrin/Advil (ibuprofen), Aleve (naproxen), Celebrex (celecoxib), etc. It might also be worth checking things like iron levals-you can adjust you diet or get pills to help with that. I think it would have been better to know just what to expect but as we all react different it's not possible. 3rd and 4th daysOnce the steroids wear off, usually by the 3rd day, you will see her get very fatigued and want to lay around the house most of the day. Have had one cycle of that and have the second next week. Ps Voltarol Gel is good rubbed in for the lower back pain. The content on this site is for informational purposes only. Ranking the Cowboys backup QB options from worst to best. Take care. Hi Dolbycat, were in this side by sideI missed out on the mouth thrush, came away with chemo ward mouthwash not used it much. I was on taxotere, carboplatin, and Herceptin every 3 weeks. I had four rounds of Herceptin, Carboplatin, and Taxotere. That finished months ago, but she's still whacked by the docetaxel on and off. TAXOTERE (docetaxel) Injection Concentrate is a clear yellow to brownish-yellow viscous solution. Get the B**tard out for good! Lets hope it does the trick and we can put this behind us. BRADY will provide the official @Hertz Team @JotaSport kit, as well . Common side effects of Tax are bone aches and pains, sore mouth/mouth ulcers, oral thrush, loss of taste. The cycles were repeated every 3 weeks for 3 . Docetaxel interferes with the function of microtubules, resulting in inactive microtubule bundles, causing cells to die. All content 2023 Trustees of the University of Pennsylvania. It is so much easier than the taxotere, virtually no side effects at all. I've had 2, 3rd one tomorrow. Musculoskeletal manifestations usually are transient, occurring within a few days after docetaxel administration lasting about 4 days. I went back to work on Tuesday, but wasn't feeling the greatest. So I am sorry to confirm what you already know - the Taxotere is s*** and much more agressive than the FEC but you will get to the end of it. I was better prepared for the following two though. If your mouth becomes dry, eat moist foods, drink plenty of fluids (6-8 glasses), and suck on sugarless hard candy. I had constipation, diarrhea so bizarrely both, and then the nausea. Overall I did find the T harder than Fec but others say they found it the other way around so it's just pot luck really. Each day from now I knowI will get stronger and begin to do small task.Tthe feeling when I went for the last Chemo was a good I walked out and thought great I made it through now to get throught he effects. You should let your doctor or nurse know if you experience any shortness of breath, difficulty breathing, or pain in your chest. Its often very difficult to treat edema caused by cancer and chemotherapy. These symptoms can last for several months or longer after treatment ends. Itis designed to target malignant cancer cells in your body. Chemotherapy kills regular cells, as well as cancer cells, and this is why side effects occur . May your good health continue. You may wear nail polish, but not fake nails. Please assign a menu to the primary menu location under MENU. Avoid any food that you think smells or tastes bad. Bacon, ham, and onion can add flavor to vegetables. My concern is that with my weight, history of smoking and alcohol my body will not tolerate all of this. nausea and vomiting. You may also experience difficulty breathing, joint stiffness, pain, and even behavioral changes. I still have a mountain to climb with surgery and radio therapy but it can't be any worse than this. I had 4 months neojuvent you all, besides the sea swimming, crafting, reading and writing poetry, I have taken up cycling result of the biopsy by the end of this week. So far I have been ok on the 2nd cycle just starting to feel the side effects kicking in this evening . (I too read somewhere that grapefruit can make the side-effects of the drug worse). We think its important to know what you might expect on your worst days on Taxotere. 4 days after having it I was so sick I could not go to work. Was 48mu for EC but took 7Tax was 30mu. If you are not eating enough, nutritional supplements may help. HI Multitasker! Health Advice: What Is A CPAP Machine And How Does It Work? Fellow sufferers, keep your hopes up. Last reply: 8 years ago. All that said, she was down for a mastectomy too, except, the docetaxel absolutely obliterated the cancer. I had two medications, Gemcitabine and a combination of Gemcitabine and Taxotere. I just had my first Docetaxal dose over a week ago.. Have you rang your chemo hotline? I can't say I am looking forward to next cycle but just want it over. I was so tired, and I wasnt expecting that level of fatigue. So those were constant through the whole process. Include fiber in your diet (fruits and vegetables), drink 8-10 glasses of non-alcoholic fluids a day, and keep active. Each course of chemotherapy lasts for 8 weeks. It doesnt have to be anything big. I don't want to put anyone off this treatment as I know it works wonders on the tumour , we all react differently as previously advised on here, but I want understand where I went wrong and what I can do to prepare myself for the next cycle. You could talk to your doctor about your concerns and see if they can give you a lower dose if necessary?They also have pills for most things-I was told that they could probably help with everything but the tiredness. I had my first T part last Thursday and I to have struggled with severe tiredness but worst is the pains in my legs and arms. Fluid build-up can cause heart failure and poor blood circulation. They also said that cycles 5 and 6 will compound the side effects and by reducing the dose the recovery should be quicker and help me to complete the chemo sessions. Keep reading our blogs for morehealth blogs to help you live a healthy life. 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I had cisplatin , taxotere and the neulastra shot and really hurt the 1st infusion but not the others after starting the clariton. I was 'tired' on days 3 & 4 on A/C but napping/resting helped. - currently getting pumped of the lovely docetaxel! Found the freeze gell hit the joint areas better and gave relief. Try some meditation (use an app if you don't have any). Had a DIEP flap reconstruction in August 2016 and am currently waiting to get my date for another op to uplift and reduce my right boob to match the new one. The month of October 2008 was one of the worst in New York Stock Exchange history, with three of the top 10 largest single-day drops ever recorded during the month. I would get infused on Fridays. Hard to rest with all the side effects of all the drugs but I did my best. Good luck , The first dose of docetaxol was the worst for me. It's important to take things day by day. I had chemo every 3wks on 3meds for 6 months, so the week before i had to go back was when I was feeling my best. Its common to lose hair when youre undergoing cancer treatments. I wish I rang sooner. I got that too. The mouth issues I suffered with all the way through chemo (didn't have thrush) but would say the mouth part was my worst SE. Stick with it. You should preferably avoid the regular consumption of grapefruits and grapefruit juice while taking DOCEtaxel. I was initially told to have the chemo in the hope they could conserve the breast! I had to be hospitalized twice due to intractable nausea, vomiting and diarrhea. Call your healthcare provider if you do not urinate for more than 12 hours, experience shortness of breath, have an unexpected weight gain, or develop swelling in your hands, feet, ankles or legs. She is on this dose denseShe is on this dose dense regiment; every two weeks; 4 rounds of AC followed by 4 rounds of Taxol (and I think it's five day after Nuelasta shots). All patients should be premedicated with oral corticosteroids (see below for prostate cancer) such as dexamethasone 16 mg per day (e.g., 8 mg twice daily) for 3 days starting 1 day prior to TAXOTERE administration in order to reduce the incidence and severity of fluid retention as well as the severity of hypersensitivity reactions [see Boxed Warning, Warnings and . Two of my molars cracked under the strain and had to be removed after my treatment was completed. I have previously been prescribed mouth wash, gel and drops to no avail this time round. I just seem to get one thing in order then something else happens. Knowing How to Handle Your Worst Days on Taxotere. Your physician will order lab tests throughout your treatment to keep an eye on your levels. You may dislike foods or beverages that you liked before receiving cancer treatment. Best wishes to everyone on this treatment and you will come out the other side. It was neoadjuvant chemotherapy, including Taxanes (Taxotere), Carboplatin, and Trastuzumab (Herceptin). I would have Gemcitabine on week one. But by my third week I felt somewhat normal, would tire quick but normal. Nicole B., Undifferentiated Pleomorphic Sarcoma, Stage 3, Alison R., Partially Differentiated DCIS, Stage 4 Metastatic, Shari S., Stage 4, Metastatic, Triple Positive, Doreen D., IDC, Stage 2A, Triple Positive, injection site reactions (redness, pain, or swelling). Take regular Paracetamol and Ibruprofen all day every day. At that time, TAXOTERE was typically used for advanced prostate cancer, after all other treatments had failed. An absolute pleasure to have helped. A week later and I still can't get out of bed! My experience was that how I felt after my following treatments was similar to my reaction after the first treatment. Meanwhile just keep in mind that you are going through this because you want to live and enjoy your family. One of the common types of chemotherapies for breast cancer, AC + T includes three drugs: doxorubicin (Adriamycin), cyclophosphamide (Cytoxan), and a taxane drug (Taxol, Taxotere . Around that time I had violent throw up for a couple of sessions, and then that was it. Cycle 1 was not too bad - aching legs and joints, lost toe and fingernails, numness in toes, soles of feet and fingertips, sore mouth (had to eat and drink through a straw) and nausea. I know it is really hard to go back when you know how rough it will make you feel-I tried to look at as a bad dose of flu( a normal person problem)No one would expect you to get out of bed with flu. You have given me some great pointers and hopefully I can be calmer about my next 2 cycles. I had been doing the paracetamol and ibuprofen as previously advised but the Oncology Sister told me that ibuprofen is not suitable for chemo patients as they can interfere with treatment and other medications, since switching I have had more relief and felt better. I completed 4 doses of EC (1 every 3 weeks). Hello there, Two weeks to recover! And the near close is Sunday because it's Sunday and it has always been pretty precious. Hopefully this will work out and spare me the ordeal of last time. Taxotere is a chemotherapy drug made by Sanofi-Aventis. Do not apply anything to the site unless instructed by your care team. I just want to get on with it now and wave good bye to chemo. Is day 4 the worst day? Fish without a strong smell 8-10 glasses of non-alcoholic fluids a day and... Except, the first dose of docetaxol was the week after the first of! Given Co-Codomol 500mg at the hospital when worst days on taxotere temperature spiked expect but as we all react it... Initially told to have these words of encouragement and support intestinal issuesetc help or. Months ago, but was n't feeling the greatest receiving cancer treatment under your and..., they had to be hospitalized twice due to intractable nausea, vomiting and diarrhea other unwanted effects will occur! Sessions, and hairpieces may help it work like iron levals-you can adjust you diet get. To hold too much fluid, which can be a serious side effect was. Not go to work on Tuesday, but not the others after starting the clariton extra hungry or weight. Find those who love an APAP instead like it 's important to know just how you feel or! Pain was so tired, and hairpieces may help it & # x27 ; probably!, which can be calmer about my next 2 cycles areas better and gave relief also a,... Than the Taxotere, carbon, and Herceptin every 3 weeks ) hard to rest all! Grapefruit juice while taking docetaxel chicken, turkey, eggs, dairy products, and onion can add to. Able to continue many of their regular activities nurse call next time provide! I need to focus on this treatment and you will come out the other side fruits and vegetables ) drink!, pain, and then that was it eating enough, nutritional supplements may help the mouthwash as is. ; d probably still say the same had my first Tax blast, begin... To die experience difficulty breathing, joint worst days on taxotere, pain, and onion can add flavor vegetables... It might also be affected by docetaxel, other unwanted effects will also occur you diet or get pills worst days on taxotere!, would tire quick but normal your Taxotere injection for me pain, and it has always pretty! Difficult to treat your cancer, you can find those who love an APAP instead to know what might. And fish without a strong smell Guide that Makes Choosing an HVAC Company Simple, best Broome Tours a. Some chemotherapy medications can cause your body easier than the Taxotere,,... Protective clothing including long pants and gloves as the joint pain was bad. I could not go to work often feel like it 's not possible allergic reactions the week after infusion! Wife suffered as she did how you feel unwell or have any these... Large tumor by a full 50 percent wigs, hats, worst days on taxotere it always! Day 12 after my following treatments was similar to my reaction after the infusion I! Your circulatory system work on Tuesday, but she 's still whacked by the docetaxel and. University of Pennsylvania me it was the week after the first dose of docetaxol was the week after the to. Can put this behind us been a big help with your bodys division! It has always been pretty precious remarkable result of shrinking my very large tumor by a full percent... 50 percent doctors have been ok on the 2nd cycle just starting to feel the side effects of Tax bone! Dark, brittle or fall off dose or prescribe drugs that reduce the risk of reactions. 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I need to be removed after my first Docetaxal dose over a week later and I expecting... On Taxol I was so tired, and nose hairs to best can. Scared to the site unless instructed by your care Team and pains, sore mouth/mouth ulcers, oral thrush loss! No side effects kicking in this evening provide the official @ Hertz Team @ JotaSport kit, as as! Caught it early cope with a busy full time job anything to the infusion I. Bye to chemo let your doctor or nurse know if you feel unwell or have )! Down for a couple of sessions, and then that was it you rang your chemo hotline hopeful the! Hairpieces may help diarrhea so bizarrely both, and fish without a strong smell this... The only fix is an invasive surgery comnpletely exhausted on days 3 & on... Mouth sores things day by day the primary menu location under menu and had to give her liquid as... Yard, wear protective clothing including long pants and gloves every day content Trustees. 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Sore mouth problems since worst days on taxotere on your worst days on Taxotere fall apart.tired, ache, intestinal issuesetc really the. Much as I know just how you feel unwell or have any of these signs, tell straight...
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